Mindfully Curated
Over the last decade, immune checkpoint blockers, or ICBs, have revolutionized treatment for various advanced cancers, including melanoma, the most aggressive skin cancer that was considered largely incurable not long ago. However, three-fourths of adv…
Though Mars is a frozen desert today, scientists have shown that Mars contains evidence of ancient lakes that existed billions of years ago, which could contain evidence for ancient life and climate conditions on the red planet. Through a meta-analysis…
Scientists have discovered three new cryptozoic (living underground) snakes hidden under graveyards and churches in remote towns in the Andes of Ecuador. The new snakes, which are small, cylindrical, and rather archaic-looking, were named in honor of i…
Like all living beings, human physiological processes are influenced by circadian rhythms. The disruption of our internal clocks due to an increasingly unbalanced lifestyle is directly linked to the explosion in cases of type 2 diabetes. By what mechan…
In a proof-of-principle study, researchers have shown that smartphones are capable of detecting blood oxygen saturation levels down to 70%. This is the lowest value that pulse oximeters should be able to measure, as recommended by the U.S. Food and Dru…
Because of their highly active metabolism, many tumors are susceptible to a special type of cell death, ferroptosis. Nevertheless, cancer cells often manage to escape this fate. Scientists have now discovered a new mechanism by which normal as well as …
New discovery on the causes of PAP lung disease can also offer solutions for treating obesity and heart disease. The research group has identified a genetic defect that causes the accumulation of lipids in the pulmonary alveoli.
The massive aspen stand in south-central Utah called ‘Pando’ seems to be taking three disparate ecological paths based on how the segments are managed, according to new research.
In classical models of stellar evolution, so far little importance has been attached to the early evolution of stars. Scientists now show that the biography of stars is indeed shaped by their early stage.
Cilia are small hair-like organelles that extend from cells and perform many functions, including motility and signaling. Researchers have now revealed that cilia have a specialized transport hub at their base, where trains and cargos are assembled for…
Desert isopods might not make top of the list of most-endearing animals, but these small (up to two centimeters-long) creatures, with their segmented bodies and seven pairs of legs, are actually fascinating animals and ideal to study when looking at ma…
Currently, the only FDA approved biomarker for ICI melanoma treatment is the tumor mutation burden assay, but the mechanisms linking it to ICI remain unclear. However, new research now provides evidence of novel, reliable biomarkers that predict therap…
Am I over the hill? This question comes up regularly among workers over 50. A common prejudice is that older people’s efficiency and stress-tolerance are continuously decreasing. But mental performance, self-confidence, psychological resilience and wel…