How pathogenic gene variants lead to heart failure
Cardiomyopathy is not a uniform disease. Rather, individual genetic defects lead to heart failure in different ways, an international consortium reports.
Mindfully Curated
Cardiomyopathy is not a uniform disease. Rather, individual genetic defects lead to heart failure in different ways, an international consortium reports.
Using the fruit fly, scientists have constructed a complete and detailed single-cell map of embryo development. This research will also help scientists pursue questions like how mutations lead to different developmental defects and provides a path to u…
Genetic analyses of baboons in Kenya reveals that most of them carry traces of hybridization in their DNA. As a result of interbreeding, about a third of their genetic makeup consists of genes from another, closely-related species. Fifty years of obser…
Investigators have identified a component in the intestine that plays a critical role in repairing damaged tissue.
Only a handful of researchers have studied why an American football flies in such a unique trajectory, rifling through the air with remarkable precision, but also swerving, wobbling, and even tumbling as it barrels downfield. Now, ballistics experts ha…
Scientists and engineers have developed a one-step method involving sandpaper and powder to make robust superhydrophobic materials.
Researchers discovered that congestion control algorithms designed to ensure multiple users sending data over a network do so fairly are actually unable to avoid situations where some users are hogging all the bandwidth.
A new study shows how a type of cells called microglia contribute to the slowdown of neuron activity seen in Alzheimer’s disease. The study found that microglia that express the APOE4 gene, one of the strongest genetic risk factors for Alzheimer’s dise…
A research group has engineered a bacterial strain capable of producing lutein. The research team applied systems metabolic engineering strategies, including substrate channeling and electron channeling, to enhance the production of lutein in an engine…
The production of ammonia, a major ingredient in fertilizers, involves greenhouse gas emissions. Scientists have quantified ways to reduce carbon impacts in this process.
To monitor heart rhythms and muscle function, doctors often attach electrodes to a patient’s skin, detecting the electrical signals that lie beneath. These impulses are vital to the early diagnosis and treatment of many disorders, but currently availab…
From the wide variety of sodas, candies and baked goods that are sold worldwide, it’s clear that people love their sweet treats. But consuming too much white table sugar or artificial sweetener can lead to health issues. In the search for a better swee…
A team of researchers have injected parasitic worms into mice to study how injured cells trigger an immune response.
Researchers have been able to successfully teach microrobots how to swim via deep reinforcement learning, marking a substantial leap in the progression of microswimming capability.
The pandemic has called attention to an issue that nursing home residents, their families and those who work in nursing homes have been aware of for a long time. Recruiting and retaining both the nursing home staff who provide the very personal care ne…
Investigators have identified genetic signatures that could predict whether tumors in patients with bladder and other cancers will respond to immunotherapy.
Accurate, continuous monitoring of nitrogen dioxide and other gases in humid environments is now possible, thanks to a new water-resistant gas sensor.
Scientists have long tried to introduce genetically engineered bacteria into the gut to treat diseases. In the past, these attempts have focused on engineering common lab strains of E. coli, which cannot compete with the native gut bacteria that are we…
Researchers generated rat sperm cells inside sterile mice using a technique called blastocyst complementation.
For the first time, scientists have designed a phage combination therapy that can precisely target and suppress gut bacteria associated with inflammatory bowel diseases (IBD). The work showcases the possibility of using phages for treating diseases ass…