How the body switches out of ‘fight’ mode

Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions. But previously, astonishingly little was known about how they exactly do that. Researchers have now explored the molecular mechanism of action in…

The genesis of our cellular skeleton, image by image

Cells contain various specialized structures — such as the nucleus, mitochondria or peroxisomes — known as ‘organelles’. Tracing their genesis and determining their structure is fundamental to understanding cell function and the pathologies linked to…

Researchers discover how we perceive bitter taste

A new study reveals the detailed protein structure of the TAS2R14, a bitter taste receptor that allows us to perceive bitter taste. In addition to solving the structure of this taste receptor, the researchers were also able to determine where bitter-ta…

Impact of aldehydes on DNA damage and aging

Researchers have discovered the connection between aldehydes, organic compounds produced by cells as part of metabolic processes, and rapid aging. Their findings indicate a potential treatment for diseases that lead to accelerated aging as well as a me…