Mindfully Curated
In an advance that could improve bladder cancer treatment, a novel combination of cretostimogene grenadenorepvec and pembrolizumab has shown remarkable efficacy in patients with Bacillus Calmette-Gu rin (BCG)-unresponsive non-muscle invasive bladder ca…
The molecules that make up the matter around us are in constant motion. What if we could harness that energy and put it to use? Over 150 years ago Maxwell theorized that if molecules’ motion could be measured accurately, this information could be used …
Using artificial intelligence technology to identify patterns of DNA fragments associated with lung cancer, researchers have developed and validated a liquid biopsy that may help identify lung cancer earlier.
The awe-inspiring process of cell division can turn a fertilized egg into a baby — or a cancerous cell into a malignant tumor. With so much at stake, nature keeps it tightly controlled in a process called the cell cycle that scientists thought they th…
Using the James Webb Space Telescope, a team of astronomers studied the properties of a planet-forming disk around a young and very low-mass star. The results reveal the richest hydrocarbon composition seen to date in a protoplanetary disk, including t…
Researchers have established the most comprehensive molecular portrait of the workings of KRAS, a key cancer-causing gene or ‘oncogene,’ and how its activities impact pancreatic cancer outcomes. KRAS is one of the most commonly mutated genes in human c…
A genetic disorder leads to an increase in bioactive lipids in the brain, resulting in an imbalance between excitation and inhibition in neural circuits and promoting mental disorders. However, treatment with an enzyme inhibitor that prevents the activ…
Nuclear pore complexes (NPCs) are channels composed of multiple proteins that ferry molecules in and out of the nucleus, regulating many critical cellular functions, such as gene expression, chromatin organization and RNA processes that influence cell …
A drug approved to treat eczema provided significant improvement in the symptoms of patients with severe itching diseases that currently have no targeted treatments, according to a new study. The drug, abrocitinib, was found to cause minimal side effec…
How hard is it to stop taking antidepressants? If countless Internet posts and a number of scientific studies are to be believed, discontinuing these medications is highly problematic, and doctors often underestimate the difficulties involved. But it i…
Limited understanding of basic ocean processes is hindering progress in marine carbon dioxide removal, with the on-going commercialization of some approaches ‘premature and misguided’. Scientists now review the climatic effectiveness of four ‘nature-ba…
Researchers have investigated the feasibility of a new home-administered treatment for binge eating disorder. The new treatment combines a gentle brain stimulation technique called transcranial direct current stimulation (tDCS) with a training program …
In a parasitic first, a Baltic amber specimen has revealed that millions of years ago tiny worms known as nematodes were living inside of and feeding on the outer protective layer of pseudoscorpions.