How a mutation in microglia elevates Alzheimer’s risk
A new study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer’s pathology in other ways.
Mindfully Curated
A new study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer’s pathology in other ways.
Children whose mothers are highly stressed, anxious or depressed during pregnancy may be at higher risk for mental health and behavior issues during their childhood and teen years, according to new research.
Immunotherapies that target the CD20 antigen have revolutionized how patients with a variety of blood cancers and hematologic disorders have been treated. However, many patients develop resistance to these treatments due to a loss of the antigen that’s…
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects neurons in the brain and spinal cord causing loss of muscle control. Scientists have now suggested a potential therapeutic strategy to tackle this pathology that has no tre…
For 40 years, chemotherapy has been the standard treatment for bladder cancer patients who can tolerate this medicine. However, the results were limited, and lasting results were rare. In recent years, two groundbreaking phase-3 clinical studies have f…
Many songbirds are nesting earlier in spring because of warmer temperatures brought about by climate change. But the shift brings another danger that is especially deadly for nestlings: greater exposure to temperature variability in the form of cold sn…
Quiz shows, where contestants answer rapid-fire questions in a high-stress, high-stakes environment, are an integral part of TV programming — and now they are demonstrating that they have research value, according to a new study.
Scientists have published new evidence that shows changes in brain network patterns that occur in early-stage Alzheimer’s disease differ from those associated with normal aging. The findings also show that the impact of Alzheimer’s on brain function is…
Researchers reveal that vitamin B12 significantly boosts the efficiency of cellular reprogramming, thus holding promise for regenerative medicine. Vitamin B12 supplementation shows potential in speeding up tissue repair in a model of ulcerative colitis…
Researchers reveal that vitamin B12 significantly boosts the efficiency of cellular reprogramming, thus holding promise for regenerative medicine. Vitamin B12 supplementation shows potential in speeding up tissue repair in a model of ulcerative colitis…
Natural carbon reservoirs will play a major role at the COP28 world climate conference in the United Arab Emirates. In a recent study, a team of more than two hundred researchers worldwide presents new estimates of the storage potential of forests arou…
Natural carbon reservoirs will play a major role at the COP28 world climate conference in the United Arab Emirates. In a recent study, a team of more than two hundred researchers worldwide presents new estimates of the storage potential of forests arou…
Common oral infections, periodontal diseases and caries, are associated with inflammatory metabolic profiles related to an increased risk of cardiometabolic diseases, a new study by an international team of researchers suggests. Oral infections also pr…
Common oral infections, periodontal diseases and caries, are associated with inflammatory metabolic profiles related to an increased risk of cardiometabolic diseases, a new study by an international team of researchers suggests. Oral infections also pr…
The return of the grey wolf (Canis lupus) to Germany, which began 23 years ago in the region of Lusatia in Eastern Germany, is a process of great ecological and social significance. Therefore, a precise understanding of the recolonization of the origin…
Investigators have developed an artificial intelligence (AI) model based on epigenetic factors that is able to predict patient outcomes successfully across multiple cancer types.
People who drink more than three liters of fluid a day may be suffering from a rare hormone deficiency. For many, however, it is just a harmless habit. Failing to differentiate the two correctly can be fatal, so researchers have been investigating what…
People who drink more than three liters of fluid a day may be suffering from a rare hormone deficiency. For many, however, it is just a harmless habit. Failing to differentiate the two correctly can be fatal, so researchers have been investigating what…
Engineers investigating the load-bearing capacity of conical shells, made from soft materials, have discovered performance-limiting weaknesses that could have implications for soft robotics — affecting the ability of morphing cones to perform fundamen…
New research has revealed that bumblebees cannot taste pesticides present in nectar, even at lethal concentrations. This means bumblebees are not able to avoid contaminated nectar, putting them at high risk of pesticide exposure and posing a threat to …