Science & Technology

A study reveals a possible explanation for why checkpoint blockade inhibitors don’t work well for some patients whose tumors have a high mutational burden.

R esearchers created a machine learning algorithm using computational topology that profiles shapes and spatial patterns in embryos to study how these cells organize themselves into tissue-like architectures. In a new study, they take that system to th…

Researchers provide essential insights on the molecular activation of the MAP kinase p38?, the final switch triggering the inflammatory response. Inflammation is a cellular coping mechanism when confronted with stress, such as an infection. However, to…

Researchers have characterized a specialized type of immune cell, which plays a key role in protecting and repairing the cells in the healthy human gut.

With research showing that the SDGs have had little political impact, the September 18-19 UN SDG Summit must pave the way for four major changes in how the SDGs are implemented and governed globally, argues an international group of sustainability expe…

Researchers have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation in specific tissues when normal methods of molecular monitoring fail. By understanding how different tissues tackle protei…

The better a songbird is at working its way around obstacles to retrieve a snack, the more complex its vocal learning ability will be.

Lab-based studies reveal how carbon atoms diffuse on the surface of interstellar ice grains to form complex organic compounds, crucial to reveal the chemical complexity in the universe.

Rivers are warming and losing oxygen faster than oceans, according to a new article. The study shows that of nearly 800 rivers, warming occurred in 87% and oxygen loss occurred in 70%.

Researchers have discovered a new way to target and kill cancer cells in hard-to-treat brain tumours using electrically charged molecules to trigger self-destruction, that could be developed into a spray treatment used during surgery.

The era of artificial-intelligence chatbots that seem to understand and use language the way we humans do has begun. Under the hood, these chatbots use large language models, a particular kind of neural network. But a new study shows that large languag…

Although a simple molecule, nitric oxide is an important signal substance that helps to reduce blood pressure by relaxing the blood vessels. But how it goes about doing this has long been unclear. Researchers now present an entirely novel principle tha…

Planetary scientists have discovered that high energy electrons in Earth’s plasma sheet are contributing to weathering processes on the Moon’s surface and, importantly, the electrons may have aided the formation of water on the lunar surface.

Researchers have found a way to harvest hydrogen from plastic waste using a low-emissions method that generates graphene as a by-product, which could help offset production costs.

In a new paper, researchers report a camera that could offer a much less expensive way to achieve ultrafast imaging for a wide range of applications such as real-time monitoring of drug delivery or high-speed lidar systems for autonomous driving. Resea…

Prioritizing career goals over fun and freedom doesn’t make your life better, researchers have found. The study across three countries discovered people who prioritized achievement over enjoyment were less happy on the next day.

It’s a skin disorder that makes life miserable for around 800 million teenagers and adults worldwide, but cientists may have found an effective treatment for acne, delivered via tiny nanoparticles.

To obtain the biggest cherry harvest, trees should be pollinated by both honey bees and mason bees. This new study shows yet another benefit of biodiversity.

Rock faces in Namibia are decorated with hundreds of stone-age images not only of animals and human footprints, but also of animal tracks. These have been largely neglected to date as researchers lacked the knowledge required to interpret them. Archaeo…

Scientists have confirmed that human brains are naturally wired to perform advanced calculations, much like a high-powered computer, to make sense of the world through a process known as Bayesian inference.