New target to beat cancer drug resistance
A novel drug target has been newly identified in the fight against drug resistance in cancer patients.
Mindfully Curated
A novel drug target has been newly identified in the fight against drug resistance in cancer patients.
A dendritic cell vaccine administered before and after autologous stem cell transplant (ASCT) was safe and immunogenic and was associated with durable clinical responses in patients with high-risk multiple myeloma.
A research team has successfully developed a new method that can prevent the crossover of large fuel molecules and suppress the degradation of electrodes in advanced fuel cell technology using methanol or formic acid. The successful sieving of the fuel…
Trigonelline is derived from coffee; researchers have found that it improves spatial learning and memory in senescence-accelerated mice. The study also suggested that this effect results from inhibiting neuroinflammation and restoring neurotransmitter …
What chemicals are we exposed to on a daily basis? That is the central question of ‘non-targeted analysis’ or NTA, an emerging field of analytical science that aims to identify all chemicals around us. A daunting task, because how can you be sure to de…
With the launch of the James Webb Space Telescope, astronomers are now able to peer so far back in time that we are approaching the epoch where we think that the first galaxies were created. Throughout most of the history of the Universe, galaxies seem…
One result of climate change is that spring is arriving earlier. However, migratory birds are not keeping up with these developments and arrive too late for the peak in food availability when it is time for breeding. By getting the birds to fly a littl…
Artificial intelligence (AI) can help plant scientists collect and analyze unprecedented volumes of data, which would not be possible using conventional methods. Researchers have now used big data, machine learning and field observations in the univers…
Galaxies from the early Universe are more like our own Milky Way than previously thought, flipping the entire narrative of how scientists think about structure formation in the Universe, according to new research.
New physics-based self-learning machines could replace the current artificial neural networks and save energy.
Maintaining a water level between 20 and 30 centimeters below the local water table will boost southern peatlands’ carbon storage and reduce the amount of greenhouse gases they release back into the atmosphere during dry periods by up to 90%, a new stu…
A research group has found a promising drug candidate for the treatment of amyotrophic lateral sclerosis (ALS). Cerebral dopamine neurotrophic factor CDNF prolongs the lifespan of and alleviates disease symptoms in rats and mice in animal studies.
Researchers have made a significant finding in determining the genetic background of dilated cardiomyopathy in Dobermanns. This research helps us understand the genetic risk factors related to fatal diseases of the heart muscle and the mechanisms under…
Research reveals new non-coding genetic variants associated with Alzheimer’s disease functioning in microglia — brain cells already implicated in the progression of this often-fatal neurodegenerative condition.
Astronomers using data from NASA’s James Webb Space Telescope have identified carbon dioxide in a specific region on the icy surface of Europa.
New research using ultra-high field 7 Tesla MRI, provides a better understanding of how light stimulates our brain and could provide new insights into how it works.
Researchers reveal rapid fluvial incision attributed to the growth of high topography in China’s Yangtze River.
When you see a familiar face upright, you’ll recognize it right away. But if you saw that same face upside down, it’s much harder to place. Now researchers who’ve studied Claudio, a 42-year-old man whose head is rotated back almost 180 degrees such tha…