Science & Technology

Researchers uncovered the role of the third intracellular loop in the G protein-coupled receptors’ signaling mechanism, which could lead to a more targeted approach to drug discovery and a paradigm shift for new therapeutics.

Researchers use a DNA designer drug to restore key protein levels in motor neurons, delaying paralysis in a mouse model of ALS.

Researchers outline the complexities of young-onset colorectal cancer and the research needed to map out a path toward understanding it.

A new process that lets scientists chemically cut apart and stitch together nanoscopic layers of two-dimensional materials — like a tailor altering a suit — could be just the tool for designing the technology of a sustainable energy future. Researche…

An artificial pancreas improves blood sugar control in children ages 2 to 6 with type 1 diabetes, according to a new study.

More donated hearts could be suitable for transplantation if they are kept functioning within the body for a short time following the death of the donor, new research has concluded.

Most cities don’t map their own pedestrian networks. Now, researchers have built the first open-source tool to let planners do just that. Researchers have built TILE2NET, an open-source tool that uses aerial imagery and image-recognition to create comp…

A new approach that delivers a ‘one-two punch’ to help T cells attack solid tumors is the focus of a preclinical study. The findings showed that targeting two regulators that control gene functions related to inflammation led to at least 10 times great…

An increasing number of U.S. interstates are set to try out an invention that could save millions of taxpayer dollars and significantly reduce traffic delays. The invention, a sensor that allows concrete to ‘talk,’ decreases construction time and how o…

A new study is providing an unprecedented examination of oxygen loss on coral reefs around the globe under ocean warming. The study captures the current state of hypoxia — or low oxygen levels — at 32 different sites, and reveals that hypoxia is alre…

In a Phase II trial, adding ipilimumab to a neoadjuvant, or pre-surgical, combination of nivolumab plus platinum-based chemotherapy, resulted in a major pathologic response (MPR) in half of all treated patients with early-stage, resectable non-small ce…

Intense fishing and over-exploitation have led to evolutionary changes in fish stocks like cod, reducing both their productivity and value on the market. These changes can be reversed by more sustainable and far-sighted fisheries management. A new stud…

New research has shown that a strong coupling of light and material increases the colour brilliance of OLED displays. This increase is independent of the viewing angle and does not affect energy efficiency.

Compass readings that do not show the direction of true north and interference with the operations of satellites are a few of the problems caused by peculiarities of the Earth’s magnetic field. The magnetic field radiates around the world and far into …

Criteria used by neurologists to assess for multiple sclerosis (MS) in adults may fail to identify the illness in children with imaging suspicious for the disease, an oversight that could delay treatment of the disease at its earliest stages, according…

Researchers have shown how energy disappears in quantum turbulence, paving the way for a better understanding of turbulence in scales ranging from the microscopic to the planetary. The team’s findings demonstrate a new understanding of how wave-like mo…

In a new study, astronomers describe how extraterrestrial life has the potential to exist on distant exoplanets inside a special area called the ‘terminator zone,’ which is a ring on planets that have one side that always faces its star and one side th…

Solar cells made from metal halide perovskites achieve high efficiencies and their production from liquid inks requires only a small amount of energy. Scientists are investigating the production process. At the X-ray source BESSY II, the group has anal…