An enhanced brain delivery of antibodies heightens the potential to treat brain diseases
The blood-brain barrier blocks the entry of antibodies into the brain. This limits the potential use of antibody therapeutics to treat brain diseases, such as brain tumors. Elsewhere in the body, more than 100 United States Food and Drug Administration…
Research reveals promising approach to enhance treatment for sleep apnea-related issues
Researchers explored innovative therapeutic strategies that could greatly advance the understanding and management of OSA-related morbidities. A groundbreaking study provides new insights into the treatment of obstructive sleep apnea (OSA) and its asso…
Seismic and infrasonic signals used to characterize Nord Stream pipeline events
A new study provides further evidence that the Nord Stream seismic signals came from a complex source. The signals lasted longer than would be expected from a single explosive source, the researchers say, and were more like the signals detected from an…
Surprise! — How the brain learns to deal with the unexpected
For children, the world is full of surprises. Adults, on the other hand, are much more difficult to surprise. And there are complex processes behind this apparently straightforward state of affairs. Researchers have been using mice to decode how reacti…
Genetic variants underlying male bisexual behavior, risk-taking linked to more children, study shows
Because same-sex sexual behavior does not result in offspring, evolutionary biologists have long wondered how the genes associated with this behavior have persisted in the human genome, and whether they will remain in the future. A new study suggests t…
Shining a light on the hidden damage of mild brain injuries
We all know someone who’s had a head injury that was ‘only’ a concussion, but even mild traumatic brain injuries can cause lasting damage, and the vast majority are never diagnosed. A team created a way to diagnose mild TBIs (mTBIs) even when MRI scans…
‘Giant’ predator worms more than half a billion years old discovered in North Greenland
Fossils of a new group of animal predators have been located in the Early Cambrian Sirius Passet fossil locality in North Greenland. These large worms may be some of the earliest carnivorous animals to have colonized the water column more than 518 mill…
Using the body’s own cells to treat traumatic brain injury
Traumatic brain injuries (TBIs) can cause lasting damage, but stopping the rampant brain inflammation they cause is difficult. A team at the Wyss, @SEAS and @MGH led by Samir Mitragotri has made a new treatment using macrophages — immune cells that mi…