Gene therapy reverses effects of autism-linked mutation in brain organoids
Scientists use lab-grown human brain tissue to identify neural abnormalities in Pitt-Hopkins Syndrome and show gene therapy tools can rescue neural structure and function.
Mindfully Curated
Scientists use lab-grown human brain tissue to identify neural abnormalities in Pitt-Hopkins Syndrome and show gene therapy tools can rescue neural structure and function.
DNA-to-protein mapping could help researchers understand some health disparities.
The absence of large herbivores after the extinction of the dinosaurs changed the evolution of plants. The 25 million years of large herbivore absence slowed down the evolution of new plant species. Defensive features such as spines regressed and fruit…
Astronomers discovered eight new echoing black hole binaries in our galaxy, enabling them to piece together a general picture of how a black hole evolves during an outburst. The findings will help scientists trace a black hole’s evolution as it feeds o…
Researchers have reported a fundamentally new approach to the structural investigation of RNA molecules. ROCK, as it is called, uses an RNA nanotechnological technique that allows it to assemble multiple identical RNA molecules into a highly organized …
Scientists have developed a tracking system that can be attached to monarch butterflies and transmit data about their location all throughout their three-month migratory journey south.
Atrial fibrillation, the most common cardiac rhythm abnormality, has been linked to one-third of ischemic strokes, the most common type of stroke. But atrial fibrillation is underdiagnosed, partly because many patients are asymptomatic.
Researchers have shown that ablation therapy, often used to correct an abnormally beating heart, could be used to correct disorders of the stomach.
A group of rare diseases called ciliopathies — polycystic kidney disease notable among them — emerge from defects in cilia. These are the tiny hairlike structures on the surface of almost every cell type. Scientists experimentally ‘knocked out,’ or g…
An international team of researchers has demonstrated a widely applicable methodology enabling a full 360° active phase modulation for metasurfaces while maintaining significant levels of uniform light amplitude. This strategy can be fundamentally appl…
Researchers have uncovered a new way to help identify babies and fetuses at high-risk of developing brain bleeds, paving the way for better early intervention.
Study of Campanula americana supports strengthening conservation efforts in glacial refugia areas because of their high genetic diversity. Conservation of those areas in the southern Appalachians and the Gulf Coast has implications for other areas of t…
Climate change is already affecting plants and animals worldwide and is a growing threat to biodiversity, adding a new layer to the existing challenges of habitat loss, invasive species, pollution, and overexploitation. A new study surveyed the recomme…
Single-cell analysis of autopsied human testes suggests that abnormalities associated with aging sperm cells might be exacerbated by elevated body mass index (BMI).
Researchers who previously discovered channels in the skull have found that cerebrospinal fluid can exit the brain through these channels to reach the skull’s bone marrow, which can detect and respond to infection or injury. Tapping into this process m…
Seagrasses play an important role in our climate. They are one of the most efficient sinks of carbon dioxide on Earth. A team of scientists now reports that seagrasses release large amounts of sugar, largely in the form of sucrose, into their soils — …
A study of nearly 9,000 children found those who eat a vegetarian diet had similar measures of growth and nutrition compared to children who eat meat. The study also found that children with a vegetarian diet had higher odds of underweight weight statu…
A new study suggests that reducing daily sedentary time can have a positive effect on the risk factors of lifestyle diseases in only three months. Spending just one hour less sitting daily and increasing light physical activity can help in the preventi…
When you first break a bone, the body sends out an inflammatory response, and cells begin to form a hematoma around the injured area. Within a week or two, that blood clot is replaced with a soft material called callus that forms a bridge of sorts that…
A research team has developed a new microfluidic chip for diagnosing diseases that uses a minimal number of components and can be powered wirelessly by a smartphone. The innovation opens the door for faster and more affordable at-home medical testing.