Predicting protein-protein interactions

Scientists have collaborated to build a structurally-motivated deep learning method built from recent advances in neural language modeling. The team’s deep-learning model, called D-SCRIPT, was able to predict protein-protein interactions (PPIs) from pr…

Unlocking the cause of UTI-induced delirium

Researchers have found that blocking the action of a protein called interleukin 6 (IL-6), part of the immune system, could resolve the delirium that often accompanies urinary tract infection (UTI) in elderly patients. Their study could pave the way for…

Building a human body through gastrulation

Researchers offer a phylogenetic and ontogenetic overview of the primitive streak and its role in mediating amniote (vertebrate animals that develop on land) gastrulation, and discuss the implications of embryonic stem cell-based models of early mammal…